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- Novartis receives FDA approval of Tekamlo, a single-pill combination of aliskiren and amlodipine to treat high blood pressure
- FDA Approves ella Tablets for Prescription Emergency Contraception
- FDA Approves Longer Use of Valcyte for Adult Kidney Transplant Patients at High Risk of Developing Cytomegalovirus (CMV) Disease
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- FDA Approves New Taxotere (docetaxel) Injection Concentrate Formulation
Happy Birthday, Viagra!!!
June 20, 2008
10 years have passed since the sensational arrival of the little blue magic pill that is known to perform wonders. For men fighting erectile dysfunction Viagra has become sort of a synonym to a pair of boxing gloves. The drug started a real sexual revolution only comparable to the one caused by the invention of contraceptive pills. In just ten years Viagra (sildenafil citrate) managed to get into the top list of the world’s best known brand names, helped almost 30 million men around the globe and it looks like there’s still way to go. 
As you might or might not know the most appreciated effect of the drug was accidentally discovered during a series of medical trials for a new hypertension medication. The impact of this ‘accident’ can hardly be overestimated, since it completely changed lives of millions of men who were just about to give up on their sexual lives. Pfizer, the manufacturer of the drug, owes a hell lot of money to the Lady Luck.
(more…)
Study Pushes Anti-Bleeding Drug off Market
May 27, 2008
A new study conducted by the Ottawa Health Research Institute provides solid evidence that patients taking the anti-bleeding drug Aprotinin (marketed under the name of Trasylol) are at higher risk of dying from post-surgery complications then those receiving cheaper generic medications.
More than 2 thousand patients from 19 heart-surgery institutions of Canada took part in the research. The findings indicate that patients receiving Trasylol were 50% more likely to die from complications than those who took two other clotting medications (Amicar or Cyklokapron). 6% of the patients receiving Trasylol died within 30-day mark after the surgery. The reason for such high death rates, however, remains unrevealed. Researchers put the blame on the clotting properties of Trasylol.
According to the co-author of the research Dr. Paul Hebert, the risk of Trasylol outweighs its benefits. Trasylol (manufacturer Bayer AG) is used to prevent excessive blood loss during high-risk heart surgeries. The drug was first approved by the FDA (U.S. Food and Drug Administration) in 1993. (more…)
Antidepressant Prescriptions Soar but Do They Really Work?
April 30, 2008
IMS Health, a market research firm, named antidepressants the most widely prescribed drugs in the U.S. with near 258 million prescriptions to 30 million patients in 2007. This arouses hot arguments on whether the number of people with depression has increased or whether the drug is simply overprescribed.
Antidepressants are a very effective medication for people with severe mental problems, but in case they are marketed too aggressively they might be used as a quick fix for even a slightest emotional difficulty.
Although they are no magical cure for all diseases, antidepressants remain among the best selling drugs with $12 billion dollar sales last year. Because of the increase in the use of this type of medications several research agencies decided to test their effectiveness.
According to British researchers who analyzed the data of 35 clinical trials of Prozac, Serzone, Paxil and Effexor, antidepressants only work for people with severe forms of depression. As for those with mild emotional problems, the effect of the drugs equals to that of placebo. The bottom-line is that many people taking antidepressants don’t really need them.
However another study financed by the National Institute of Mental Health showed that taking more than one antidepressant or switching to a different medication in case the previous one didn’t work can effectively treat chronic depressions. (more…)
Generic Nimotop
April 10, 2008
Nimodipine is used for:
Reducing problems due to lack of oxygen caused by bleeding from a blood vessel in the brain. It may also be used for other conditions as determined by your doctor.
Nimodipine is a calcium channel blocking agent. Exactly how Nimodipine works is unknown.
Do NOT use Nimodipine if:
- you are allergic to any ingredient in Nimodipine
Contact your doctor or health care provider right away if any of these apply to you.
Before using Nimodipine :
Some medical conditions may interact with Nimodipine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver problems, heart problems (eg, slow heartbeat), shock due to serious heart problems, low blood pressure, fluid in your lungs, or if you have a history of heart attack
Some MEDICINES MAY INTERACT with Nimodipine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Calcium channel blockers (eg, amlodipine) or other blood pressure medicines because actions and side effects may be increased by Nimodipine
This may not be a complete list of all interactions that may occur. Ask your health care provider if Nimodipine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
